TOPAZ1 Antibody
| Code | Size | Price |
|---|
| PSI-7737-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7737-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TOPAZ1 Antibody: C3orf77, C3orf77, Testis- and ovary-specific PAZ domain-containing protein 1
Application Note:
TOPAZ1 antibody can be used for detection of TOPAZ1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
The testis and ovary specific PAZ domain containing 1 (TOPAZ1) protein is a highly conserved protein that is highly expressed in the gonads during germ cell meiosis, suggesting that it may play a role in germ cell development (1). It contains a PAZ domain and a zinc finger domain and is exclusively expressed in adult testis and fetal ovary.
Background References:
- Baillet A, Le Bouffant R, Volff JN, et al. TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates. PLoS One 2011; 6:e26950.
Buffer:
TOPAZ1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (88%), Sheep: (88%)
Immunogen:
TOPAZ1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TOPAZ1.
The immunogen is located within amino acids 1330 - 1380 of TOPAZ1.
The immunogen is located within amino acids 1330 - 1380 of TOPAZ1.
NCBI Gene ID #:
375337
NCBI Official Name:
testis and ovary specific PAZ domain containing 1
NCBI Official Symbol:
TOPAZ1
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 65, 186 kDa
Observed: 60, 240 kDa
Observed: 60, 240 kDa
Protein Accession #:
NP_001138502
Protein GI Number:
222537754
Purification:
TOPAZ1 antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
TOPAZ1 antibody is human, mouse and rat reactive. At least three isoforms of TOPAZ1 are known to exist.
Swissprot #:
Q8N9V7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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