AMCA-H
| Code | Size | Price |
|---|
| CDX-A0009-M100 | 100 mg | £70.00 |
Quantity:
| CDX-A0009-M500 | 500 mg | £194.00 |
Quantity:
| CDX-A0009-G002 | 2 g | £561.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C
Documents
Further Information
Alternate Names/Synonyms:
7-Amino-4-methyl-3-coumarinylacetic acid
Appearance:
Brown solid.
CAS:
106562-32-7
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15)
InChiKey:
QEQDLKUMPUDNPG-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 106562-32-7. Formula: C12H11NO4. MW: 233.22. Synthetic. AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling (Ex/Em: 353/455nm). It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stoke's shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and triple labeling in immunofluorescence microscopy, arrays and in situ hybridization. NHS-AMCA and Sulfo-NHS-AMCA are reactive towards primary amine groups on antibodies, proteins, peptides and other biomolecules. AMCA-Hydrazide is used to label glycosylation sites or for conjugation to carboxyl groups using the crosslinker EDC.
MDL:
MFCD00081051
Molecular Formula:
C12H11NO4
Molecular Weight:
233.22
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling (Ex/Em: 353/455nm). It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stoke's shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and triple labeling in immunofluorescence microscopy, arrays and in situ hybridization. NHS-AMCA and Sulfo-NHS-AMCA are reactive towards primary amine groups on antibodies, proteins, peptides and other biomolecules. AMCA-Hydrazide is used to label glycosylation sites or for conjugation to carboxyl groups using the crosslinker EDC.
Purity:
>90% (HPLC)
Signal word:
Warning
SMILES:
CC1=C(CC(O)=O)C(=O)OC2=C1C=CC(N)=C2
Solubility Chemicals:
Soluble in DMSO or DMF.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) G-L. Ferri et al.; J. Histochem. Cytochem. 45(2), 155 (1997) | (2) B. Ufhake et al.; J. Neurosc. Meth. 40(1), 39 (1991) | (3) M. W. Wessendorf et al.; J. Histochem. Cytochem. 38(1), 87 (1990)
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