10-Acetyl-3,7-dihydroxyphenoxazine

Chemodex
Product Code: CDX-A0022
Supplier: Chemodex
CodeSizePrice
CDX-A0022-M02525 mg£242.00
Quantity:
CDX-A0022-M200200 mg£1,478.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
Amplex® Red (Registered trademark of LifeTechnologies)
Appearance:
Solid.
CAS:
119171-73-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3
InChiKey:
PKYCWFICOKSIHZ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 119171-73-2. Formula: C14H11NO4. MW: 257.24. Synthetic. 10-acetyl-3,7-dihydroxyphenoxazin (Amplex Red) is a non-fluorescent, highly sensitive and stable probe for H2O2. Amplex Red is an applicable as a fluorogenic substrate for peroxidase. In the presence of horseradish peroxidase (HRP), the Amplex Red reagent reacts in a 1:1 stechiometry with H2O2 to produce highly fluorescent resorufin. Because H2O2 is produced in many different enzymatic reactions, the Amplex Red reagent allows researchers to detect the activity of many different enzymes. 10-acetyl-3,7-dihydroxyphenoxazin has absorption and fluorescence emission maxima of approximately 563 nm and 587 nm, respectively, and because its extinction coefficient is high (54,000 cm-1M-1), the assay can be performed either fluorometrically or spectrophotometrically.
MDL:
MFCD00467861
Molecular Formula:
C14H11NO4
Molecular Weight:
257.24
Package Type:
Vial
Precautions:
P264, P270, P301, P312, P330
Product Description:
10-acetyl-3,7-dihydroxyphenoxazin (Amplex Red) is a non-fluorescent, highly sensitive and stable probe for H2O2. Amplex Red is an applicable as a fluorogenic substrate for peroxidase. In the presence of horseradish peroxidase (HRP), the Amplex Red reagent reacts in a 1:1 stechiometry with H2O2 to produce highly fluorescent resorufin. Because H2O2 is produced in many different enzymatic reactions, the Amplex Red reagent allows researchers to detect the activity of many different enzymes. 10-acetyl-3,7-dihydroxyphenoxazin has absorption and fluorescence emission maxima of approximately 563 nm and 587 nm, respectively, and because its extinction coefficient is high (54,000 cm-1M-1), the assay can be performed either fluorometrically or spectrophotometrically.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
CC(=O)N1C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2
Solubility Chemicals:
Soluble in DMSO or DMF.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) I. Snyrychova et al.; Phys. Plantarum, 135(1), 1-18 (2009) | (2) J.G. Montay et al.; J. Immunol. Meth. 202, 133 (1997) | (3) M. Zhou et al.; Anal. Biochem. 253, 162 (1997)