6-(4-Acetamido-1,8-naphthalamido) hexanoic acid

Chemodex
Product Code: CDX-A0038
Supplier: Chemodex
CodeSizePrice
CDX-A0038-M01010 mg£78.00
Quantity:
CDX-A0038-M05050 mg£189.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C

Images

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Chemical Structure

Chemical Structure

Further Information

Appearance:
Solid.
CAS:
172227-59-7
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C20H20N2O5/c1-12(23)21-16-10-9-15-18-13(16)6-5-7-14(18)19(26)22(20(15)27)11-4-2-3-8-17(24)25/h5-7,9-10H,2-4,8,11H2,1H3,(H,21,23)(H,24,25)
InChiKey:
RCZAYEHQRFPFSH-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 172227-59-7. Formula: C20H20N2O5. MW: 368.38. Synthetic. The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained importance, not only for medical diagnostics or clinical genetics, but also detection and isolation of DNA for research purposes. The pentamethylene chain in 6 acts as a linker molecule and keeps the target at a reasonable distance to avoid direct interaction with oligonucleotides.
MDL:
MFCD04040049
Molecular Formula:
C20H20N2O5
Molecular Weight:
368.38
Package Type:
Vial
Product Description:
The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained importance, not only for medical diagnostics or clinical genetics, but also detection and isolation of DNA for research purposes. The pentamethylene chain in 6 acts as a linker molecule and keeps the target at a reasonable distance to avoid direct interaction with oligonucleotides.
Purity:
>95% (HPCE)
SMILES:
CC(=O)NC1=CC=C2C(=O)N(CC(O)=O)C(=O)C3=C2C1=CC=C3
Solubility Chemicals:
Soluble in water or DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) K. Misra et al.; Radiobiol. Bio-Med. Res. 129 (2004) | (2) R.W. Odd et al.; Blackwell Scientific Publication, 317 (1992) | (3) R.J. Kaiser et al.; Nucleic Acids Research 17, 6087 (1989)