5-ROX
| Code | Size | Price |
|---|
| CDX-C0004-M020 | 20 mg | £159.00 |
Quantity:
| CDX-C0004-M200 | 200 mg | £1,004.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4 °C
Documents
Further Information
Alternate Names/Synonyms:
5-Carboxy-X-rhodamine; 5-CXR
Appearance:
Green solid.
CAS:
216699-35-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C33H30N2O5/c36-32(37)20-9-10-21(24(17-20)33(38)39)27-25-15-18-5-1-11-34-13-3-7-22(28(18)34)30(25)40-31-23-8-4-14-35-12-2-6-19(29(23)35)16-26(27)31/h9-10,15-17H,1-8,11-14H2,(H-,36,37,38,39)
InChiKey:
UNGMOMJDNDFGJG-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 216699-35-3. Formula: C33H30N2O5. MW: 534.6. Synthetic. 5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates. Used for oligonucleotide labeling and automated DNA sequencing applications.
MDL:
MFCD28355897
Molecular Formula:
C33H30N2O5
Molecular Weight:
534.6
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates. Used for oligonucleotide labeling and automated DNA sequencing applications. ROX is a passive fluorescent dye used in real-time PCR (qPCR) for signal normalisation. By normalising the fluorescent signal, this can reduce the variability between technical replicates.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
OC(=O)C1=CC=C(C(=C1)C([O-])=O)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34
Solubility Chemicals:
Soluble in methanol, DMSO or DMF.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) P.J. Finn et al.; Nucleic Acids Res. 30, 2877 (2002) | (2) J.M. Bartlett et al.; Mol Biotechnol 13, 185 (1999) | (3) S.C. Hung et al.; Anal Biochem 255, 32 (1998)
Related Products
| Product Name | Product Code | Supplier | (5(6)-ROX | CDX-C0012 | Chemodex | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5(6)-ROX N-succinimidyl ester | CDX-C0013 | Chemodex | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||