4-Di-2-ASP
Code | Size | Price |
---|
CDX-D0012-G001 | 1 g | £158.00 |
Quantity:
CDX-D0012-G005 | 5 g | £568.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4 °C
Images
Documents
Further Information
Alternate Names/Synonyms:
4-(4-Diethylaminostyryl)-1-methylpyridinium iodide; DiASP
Appearance:
Dark red crystalline powder.
CAS:
105802-46-8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C18H23N2.HI/c1-4-20(5-2)18-10-8-16(9-11-18)6-7-17-12-14-19(3)15-13-17;/h6-15H,4-5H2,1-3H3;1H/q+1;/p-1
InChiKey:
WIPKWLIHFGTFQV-UHFFFAOYSA-M
Long Description:
Chemical. CAS: 105802-46-8. Formula: C18H23IN2. MW: 394.29. Synthetic. Some cationic mitochondrial dyes such as 4-Di-1-ASP and 4-Di-2-ASP stain presynaptic nerve terminals independent of neuronal activity. The photostable 4-Di-2-ASP dye, which is nontoxic to cells, has been employed to stain living nerve terminals in rabbit corneal epithelium, in rat epidermis and at mouse, snake and frog neuromuscular junctions, as well as to visualize the innervation of the human choroid and whole mounts of the gastrointestinal tract. Methods for using 4-Di-2-ASP to image neuronal cells in live animals have been described (Ex/Em = 488/607 nm).
MDL:
MFCD00031908
Molecular Formula:
C18H23IN2
Molecular Weight:
394.29
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
Some cationic mitochondrial dyes such as 4-Di-1-ASP and 4-Di-2-ASP stain presynaptic nerve terminals independent of neuronal activity. The photostable 4-Di-2-ASP dye, which is nontoxic to cells, has been employed to stain living nerve terminals in rabbit corneal epithelium, in rat epidermis and at mouse, snake and frog neuromuscular junctions, as well as to visualize the innervation of the human choroid and whole mounts of the gastrointestinal tract. Methods for using 4-Di-2-ASP to image neuronal cells in live animals have been described (Ex/Em = 488/607 nm).
Purity:
>97% (NMR)
Signal word:
Warning
SMILES:
[I-].CCN(CC)C1=CC=C(C=CC2=CC=[N+](C)C=C2)C=C1
Solubility Chemicals:
Soluble in DMSO, DMF or chloroform.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) C. Seebacher et al.; Adv. Mat. 13(18), 1374 (2001) | (2) R.S. Wilkinson et al.; J. Neurosci. 14, 3319 (1994) | (3) L. Chen et al.; J. Neurosci. 14, 796 (1994) | (4) M.B. MacIver et al.; J. Neurosci. 13, 4511 (1993) | (5) A.A. Herrera et al.; J. Neurocytol. 19, 67 (1990) | (6) C.A. Nurse et al.; Cell Tissue Res. 255, 125 (1989) | Thyroid hormone coordinates developmental trajectories but does not underlie developmental truncation in danionins: Y. Hu, et al.; Dev. Dyn. 248, 1144 (2019)
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