DAF-2 DA

Chemodex
Product Code: CDX-D0085
Supplier: Chemodex
CodeSizePrice
CDX-D0085-M0011 mg£267.00
Quantity:
CDX-D0085-M0055 mg£1,036.00
Quantity:
CDX-D0085-M01010 mg£1,842.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
4,5-Diaminofluorescein diacetate; 5,6-Diaminofluorescein diacetate
Appearance:
Off-white powder.
CAS:
205391-02-2
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C24H18N2O7/c1-11(27)30-13-3-5-16-21(7-13)32-22-8-14(31-12(2)28)4-6-17(22)24(16)18-10-20(26)19(25)9-15(18)23(29)33-24/h3-10H,25-26H2,1-2H3
InChiKey:
PTSUYDXEEKDBQU-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 205391-02-2. Formula: C24H18N2O7. MW: 446.41. Synthetic. DAF-2 DA is probably the most successful indicator for nitric oxide. As with other fluorescein diacetates, DAF-2 diacetate is membrane permeant and is deacetylated by intracellular esterases to 4,5-diaminofluorescein (DAF-2). Can be used for the fluorimetric detection of nitric oxide and in fluorescence microscopy to measure real-time changes in nitric oxide levels in vivo. Spectral Data: lambdaex 491nm; lambdaem 513nm.
MDL:
MFCD05865101
Molecular Formula:
C24H18N2O7
Molecular Weight:
446.41
Package Type:
Vial
Product Description:
DAF-2 DA is probably the most successful indicator for nitric oxide. As with other fluorescein diacetates, DAF-2 diacetate is membrane permeant and is deacetylated by intracellular esterases to 4,5-diaminofluorescein (DAF-2). Can be used for the fluorimetric detection of nitric oxide and in fluorescence microscopy to measure real-time changes in nitric oxide levels in vivo. Spectral Data: lambdaex 491nm; lambdaem 513nm.
Purity:
>98% (HPLC)
SMILES:
CC(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=C1C=C(N)C(N)=C3)C1=CC=C(OC(C)=O)C=C1O2
Solubility Chemicals:
Soluble in DMSO (5mM stock solution).
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) V.M. Dirsch et al.; Biol. Proc. Online 5(1), 136 (2003) | (2) N. Nagata et al.; J. Biochem. 125(4), 658 (1999) | (3) H. Kojima et al.; Anal. Chem. 70(13), 2446 (1998) | (4) H. Kojima et al.; Chem. Pharm. Bull. 46, 373 (1998) | (5) H. Kojima et al.; Neuroreport 9, 3345 (1998)

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