3-(2-Furoyl)quinoline-2-carboxaldehyde

Chemodex
Product Code: CDX-F0001
Supplier: Chemodex
CodeSizePrice
CDX-F0001-M01010 mg£145.00
Quantity:
CDX-F0001-M05050 mg£529.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
FQ; FQCA; ATTO-TAG™ FQ Derivatization Reagent
Appearance:
White to off-white powder.
CAS:
126769-01-5
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302, H315, H319, H335
InChi:
InChI=1S/C15H9NO3/c17-9-13-11(15(18)14-6-3-7-19-14)8-10-4-1-2-5-12(10)16-13/h1-9H
InChiKey:
PNCHURHVMDRFTR-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 126769-01-5. Formula: C15H9NO3. MW: 251.24. Synthetic. 3-(2-Furoyl)quinoline-2-carboxaldehyde (FQCA) is a fluorogenic derivatizing reagent for liquid chromatography suitable for high-sensitivity analysis of amino acids by laser-induced fluorescence with an argon-ion laser. The reagent forms highly fluorescent isoindoles upon reaction with primary amines. It is used for the determination of isoelectronic points (pI values) of proteins with laser-induced fluorescence detection (c-IEF-LIF). C-IEF-LIF technique can routinely detect 10-11 M of FQCA-labeled protein, compared with 10-7 M by traditional slab gel IEF and silver staining.
MDL:
MFCD03427748
Molecular Formula:
C15H9NO3
Molecular Weight:
251.24
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
3-(2-Furoyl)quinoline-2-carboxaldehyde (FQCA) is a fluorogenic derivatizing reagent for liquid chromatography suitable for high-sensitivity analysis of amino acids by laser-induced fluorescence with an argon-ion laser. The reagent forms highly fluorescent isoindoles upon reaction with primary amines. It is used for the determination of isoelectronic points (pI values) of proteins with laser-induced fluorescence detection (c-IEF-LIF). C-IEF-LIF technique can routinely detect 10-11 M of FQCA-labeled protein, compared with 10-7 M by traditional slab gel IEF and silver staining. Spectral Data: lambdaex=~480nm, lambdaem=~590nm.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
[H]C(=O)C1=NC2=CC=CC=C2C=C1C(=O)C1=CC=CO1
Solubility Chemicals:
Soluble in methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) D. Pinto et al.; J. Chrom. B 793(1), 107 (2003) | (2) D.P. Richards et al.; J. Chromatog. A. 853, 21 (1999) | (3) I.H. Lee et al.; Anal. Chem. 70, 4546 (1998) | (4) D.B. Craig et al.; Electrophoresis 19, 2175 (1998) | (5) S.C. Beale et al.; J. Chromatog. 499, 579 (1990)

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