7-Methoxycoumarin-3-carboxylic acid
| Code | Size | Price |
|---|
| CDX-M0016-M500 | 500 mg | £151.00 |
Quantity:
| CDX-M0016-G005 | 5 g | £1,058.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C
Documents
Further Information
Alternate Names/Synonyms:
7-Methoxy-2-oxo-2H-1-benzopyran-3-carboxylic acid
Appearance:
White to off-white solid.
CAS:
20300-59-8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C11H8O5/c1-15-7-3-2-6-4-8(10(12)13)11(14)16-9(6)5-7/h2-5H,1H3,(H,12,13)
InChiKey:
VEEGNDSSWAOLFN-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 20300-59-8. Formula: C11H8O5. MW: 220.18. Synthetic. An amine-reactive blue fluorescent probe that provides a distinguishable contrast when used with longer-wavelength probes in certain multicolor fluorescence applications such as nucleic acid and protein microarrays, in situ hybridization and immunofluorescence. This carboxylic acid derivative of 7-methoxycoumarin can be used for coupling to amines, hydrazines or hydroxylamines on biomolecules of interest. Spectral data: Ex=336nm, Em=402nm (Buffer, pH9).
MDL:
MFCD00452770
Molecular Formula:
C11H8O5
Molecular Weight:
220.18
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
An amine-reactive blue fluorescent probe that provides a distinguishable contrast when used with longer-wavelength probes in certain multicolor fluorescence applications such as nucleic acid and protein microarrays, in situ hybridization and immunofluorescence. This carboxylic acid derivative of 7-methoxycoumarin can be used for coupling to amines, hydrazines or hydroxylamines on biomolecules of interest. Spectral data: Ex=336nm, Em=402nm (Buffer, pH9).
Purity:
>97% (HPCE)
Signal word:
Warning
SMILES:
COC1=CC2=C(C=C1)C=C(C(O)=O)C(=O)O2
Solubility Chemicals:
Soluble in DMSO, DMF or acetonitrile.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) T. Berthelot, et al.; J. Fluoresc. 14, 671 (2004) | (2) Y. Ma, et al.; J. Med. Chem. 47, 6349 (2004) | (3) M. Hagihara, et al.; JACS 128, 12932 (2006) | (4) H. Tetsuia, et al.; Pep. Sci. 43, 349 (2006) | (5) A.R. Katritzky, et al.; Synthesis 2011, 83 (2011) | (6) A.R. Katritzky, et al.; Synthesis 2011, 1494 (2011) | (7) L.T. Tegler, et al.; Angew. Chem. Int. Ed. 50, 1823 (2011)
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