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Chemodex

NBD-PZ

Product Code:
 
CDX-N0014
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
-20 °C
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Chemical Structure
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Chemical Structure

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CodeSizePrice
CDX-N0014-M200200 mg£167.00
Quantity:
CDX-N0014-G0011 g£572.00
Quantity:
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
4-Nitro-7-piperazino benzofurazan
Appearance:
Red to brown powder.
CAS:
139332-66-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302, H315, H319, H335
InChi:
InChI=1S/C10H11N5O3/c16-15(17)8-2-1-7(9-10(8)13-18-12-9)14-5-3-11-4-6-14/h1-2,11H,3-6H2
InChiKey:
MVLWYDGJBGPXOL-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 139332-66-4. Formula: C10H11N5O3. MW: 249.23. Synthetic. Fluorescent reagent for the determination of mono- and diisocyantes in air samples, and determination of lactate, hydroxybutyrate and other intermediates in body fluids. The piperazino moiety reacts readily with isocyantes to form the corresponding urea-derivatives. The derivatives can be detected by LC with UV or fluorescent-detection. Used for visualizing lysosomes in living cells also.
MDL:
MFCD00191507
Molecular Formula:
C10H11N5O3
Molecular Weight:
249.23
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
This common fluorescent reagent often used in carbohydrate analysis, is also useful in fluorescence visualization of lysosomes in live cell lines in culture. This fluorophore that has the unusual environmentally sensitive property of increasing fluorescence in low pH environments. Comparison of staining patterns with the common LysoTracker™ or LysoSensor™ dyes indicated comparable staining, albeit using a higher concentration of NBD-piperazine (1 µM versus 100 nM for the MP dyes) but at a lower cost per assay. Also used for the determination of mono- and diisocyantes in air samples, and determination of lactate, hydroxybutyrate and other intermediates in body fluids. The piperazino moiety reacts readily with isocyantes to form the corresponding urea-derivatives. The derivatives can be detected by LC with UV or fluorescent-detection. Spectral data: lambdaex=470nm, lambdaem=540nm.
Purity:
>99% (HPLC)
Signal word:
Warning
SMILES:
[O-][N+](=O)C1=CC=C(N2CCNCC2)C2=NON=C12
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) T.M. Toyo'oka, et al.; J. Chromatogr. 588, 61 (1991) | (2) T.M. Toyo'oka, et al.; Anal. Chim. Acta 465, 111 (2002) | (3) T. Santa, et al.; Biomed. Chromatogr. 16, 523 (2002) | (4) M. Vogel et al.; Anal. Chem. 74, 6418 (2002) | (5) A. Ostin et al.; J. Environ. Monit. 5, 100 (2003) | (6) J.-A. Lee et al.; Analytica Chimica Acta 534(2), 185 (2005) | (7) K. Ishiguro et al.; BioTechniques 45(4), 465 (2008)