JC-1
| Code | Size | Price |
|---|
| CDX-T0046-M010 | 10 mg | £291.00 |
Quantity:
| CDX-T0046-M100 | 100 mg | £1,475.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C
Documents
Further Information
Alternate Names/Synonyms:
JC-1 jodide
Appearance:
Dark violet solid.
CAS:
3520-43-2
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
InChiKey:
FYNNIUVBDKICAX-UHFFFAOYSA-M
Long Description:
Chemical. CAS: 3520-43-2. Formula: C25H27Cl4IN4. MW: 652.23. Synthetic. A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.
MDL:
MFCD00188475
Molecular Formula:
C25H27Cl4IN4
Molecular Weight:
652.23
Package Type:
Vial
Product Description:
A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.
Purity:
>90% (HPLC)
SMILES:
[I-].CCN1C(=CC=CC2=[N+](CC)C3=C(C=C(Cl)C(Cl)=C3)N2CC)N(CC)C2=C1C=C(Cl)C(Cl)=C2
Solubility Chemicals:
Soluble in methanol, DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) G.Y. Guralchuk et al.; J. Phys. Chem. C 112(38), 14762 (2008) | (2) S.T. Smiley et al.; PNAS 88, 3671 (1991) | (3) M. Reers, et al.; Biochem. 30, 4480 (1991)
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