Zinpyr-1
| Code | Size | Price |
|---|
| CDX-Z0001-M020 | 20 mg | £220.00 |
Quantity:
| CDX-Z0001-M125 | 125 mg | £1,105.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20 °C
Documents
Further Information
Alternate Names/Synonyms:
ZP-1; 4',5'-Bis[bis(2-pyridylmethyl)aminomethyl]-2',7'-dichlorofluorescein
Appearance:
Salmon pink powder.
CAS:
288574-78-7
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C46H36Cl2N6O5/c47-39-21-37-43(34(41(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30)58-44-35(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)42(56)40(48)22-38(44)46(37)36-16-2-1-15-33(36)45(57)59-46/h1-22,55-56H,23-28H2
InChiKey:
QZKKSPLNXQJQRQ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 288574-78-7. Formula: C46H36Cl2N6O5. MW: 823.72. Synthetic. Membrane permeable fluorophore suitable for the fluorometric detection of Zn2+. In living cells Zinpyr-1 mainly stains the Golgi or a Golgi-associated vesicle.
MDL:
MFCD04039712
Molecular Formula:
C46H36Cl2N6O5
Molecular Weight:
823.72
Package Type:
Vial
Product Description:
Membrane permeable fluorescein-based probe suitable for the fluorometric detection of Zn2+. In living cells Zinpyr-1 mainly stains the Golgi or a Golgi-associated vesicle. It undergoes a shift in excitation from 515 to 507nm with increasing zinc concentrations using an emission filter over 513-558nm. A stock solution of 1mM (823µg/ml) should be prepared to stain brain sections. This stock solution can be further diluted in 0.9% saline to get a working solution with a final concentration of 10-20µM.
Purity:
>98% (HPLC)
SMILES:
OC1=C(CN(CC2=CC=CC=N2)CC2=NC=CC=C2)C2=C(C=C1Cl)C1(OC(=O)C3=C1C=CC=C3)C1=CC(Cl)=C(O)C(CN(CC3=CC=CC=N3)CC3=NC=CC=C3)=C1O2
Solubility Chemicals:
Soluble in DMSO (1mg/ml).
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) G.K. Walkup, et al; JACS 122, 5644 (2000) | (2) S.C. Burdette, et al.; JACS 123, 7831 (2001) | (3) C.C. Woodproof, et al.; Chem. Biol. 11, 1659 (2004) | (4) M. Malavolta, et al.; Cytometry Part A 69A, 1043 (2006) | (5) S.A. Sinclair, et al.; New Phytologist 174, 39 (2007)
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