STAT5A Antibody

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ProSci
Product Code: PSI-79-126
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-126-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from K562 cells untreated or treated with IL-4 using STAT5A (Phospho-Ser780).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT5A (Phospho-Ser780).
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Western blot analysis of lysed extracts from K562 cells untreated or treated with IL-4 using STAT5A (Phospho-Ser780).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT5A (Phospho-Ser780).

Documents

Further Information

Additional Names:
MGF, STAT5, JAK1A, JAK1B, MGF, MPF, Mammary gland factor, STA5ASTAT5
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Background References:
  • Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369. Dentelli P, et al. (1999) J Immunol. 163: 2151-2159. Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
STAT5A (Phospho-Ser780) antibody was raised against a peptide sequence around phosphorylation site of serine 780 (R-L-S (p) -P-P) derived from Human STAT5A.
Modifications:
Phospho-Specific
NCBI Gene ID #:
6776
NCBI Official Name:
signal transducer and activator of transcription 5A
NCBI Official Symbol:
STAT5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
NP_003143.2
Protein GI Number:
21618342
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of STAT5A only when phosphorylated at serine 780.
Swissprot #:
P42229