NALP3 (Nalpy3-b) Monoclonal Antibody

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ProSci
Product Code: PSI-XA-1033
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-XA-1033-0.1mg0.1mg£657.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
NALP3 antibody can be stored at 4˚C, stable for one year.

Documents

Further Information

Application Note:
NALP3 antibody can be used to recognize human NALP3. It detects endogenous protein by Immunoprecipitation (1:50) and Western Blot (1:1,000). This product is for research use only.
Background References:
  • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder: L. Agostini, et al.; Immunity 20, 319 (2004).
  • Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation: M. Chamaillard, et al.; Cell. Microbiol. 5, 581 (2003).
  • Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties: W. O'Connor, Jr., et al.; J. Immunol. 171, 6329 (2003).
  • Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases: F. Martinon and J. Tschopp; Cell 117, 561 (2004).
Buffer:
PBS containing 0.02% sodium azide
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NALP3 (monoclonal Nalpy3-b) antibody was raised against recombinant human NALP3.
NCBI Gene ID #:
114548
NCBI Official Name:
NLR family, pyrin domain containing 3
NCBI Official Symbol:
NLRP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
NALP3 (monoclonal Nalpy3-b) antibody was purified from concentrated hybridoma tissue culture supernatant. NALP3 (monoclonal Nalpy3-b) antibody was purified to ≥95% in SDS-PAGE.
Research Area:
Apoptosis
Swissprot #:
Q96P20
User NOte:
Optimal dilutions for each application to be determined by the researcher.