ALAS2 Antibody
| Code | Size | Price |
|---|
| PSI-29-663-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ALAS2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
ALAS2, ANH1, ASB, PRO2399, XLSA, ALASE, XLDPP, XLEPP, ALAS-E
Application Note:
ALAS2 antibody can be used for detection of ALAS2 by ELISA at 1:62500. ALAS2 antibody can be used for detection of ALAS2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
- Astner, I., (2005) EMBO J. 24 (18), 3166-3177.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALAS2.
NCBI Gene ID #:
212
NCBI Official Name:
aminolevulinate, delta-, synthase 2
NCBI Official Symbol:
ALAS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa, 65 kDa, 61 kDa, 63 kDa
Protein Accession #:
NP_001033058
Protein GI Number:
189217859
Purification:
Antibody is purified by protein A chromatography method.
Swissprot #:
P22557
User NOte:
Optimal dilutions for each application to be determined by the researcher.