Bcr Antibody

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ProSci
Product Code: PSI-79-194
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-194-0.1mg0.1mg£488.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from K562 cells untreated or treated with H2O2 using Bcr (Phospho-Tyr177).
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Immunohistochemical analysis of paraffin-embedded human tonsil tumor tissue using Bcr (Phospho-Tyr177).
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Western blot analysis of lysed extracts from K562 cells untreated or treated with H2O2 using Bcr (Phospho-Tyr177).
Immunohistochemical analysis of paraffin-embedded human tonsil tumor tissue using Bcr (Phospho-Tyr177).

Documents

Further Information

Additional Names:
ALL, CML, PHL, BCR1, D22S11, D22S662, CFL, BCR, BCR protein
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
Background References:
  • Sattler M, et al. Mol Cell Biol. 1999 Nov; 19 (11): 7473-7480. Li S et al. EMBO J. 2001 Dec 3; 20 (23): 6793-6804. Million RP, et, al. Mol Cell Biol. 2004 Jun; 24 (11): 4685-4695. Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006; 281: 30907 ? 30916.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Bcr (Phospho-Tyr177) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y (p) -V-N) derived from Human Bcr.
Modifications:
Phospho-Specific
NCBI Gene ID #:
613
NCBI Official Name:
breakpoint cluster region
NCBI Official Symbol:
BCR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
210 kDa
Protein Accession #:
NP_004318.3
Protein GI Number:
82546843
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Cell Cycle
SPECIFICITY:
This antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 177.
Swissprot #:
P11274