JAK2 Antibody

Contact us
ProSci
Product Code: PSI-79-174
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-174-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

1 / 2
Western blot analysis of lysed extracts from HT29 cells untreated or treated with IL-4 using JAK2 (Phospho-Tyr1007).
2 / 2
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JAK2 (Phospho-Tyr1007).
❮❯

Western blot analysis of lysed extracts from HT29 cells untreated or treated with IL-4 using JAK2 (Phospho-Tyr1007).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JAK2 (Phospho-Tyr1007).

Documents

Further Information

Additional Names:
JTK10, THCYT3, AFX, AFX1, MLLT7, JAK-2, JAK2, Janus kinase 2, kinase Jak2
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Plays a role in leptin signaling and control of body weight
Background References:
  • James C, et al. (2005) Nature. 434 (7037): 1144-1148. Argetsinger LS, et al. (2004) Mol Cell Biol. 24 (11): 4955-4967. Ungureanu D, et al. (2002) Mol Cell Biol. 22 (10): 3316-3326. Xie S, et al. (2001) Oncogene. 20 (43): 6188-6195.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
JAK2 (Phospho-Tyr1007) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1007 (K-E-Y (p) -Y-K) derived from Human JAK2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3717
NCBI Official Name:
Janus kinase 2
NCBI Official Symbol:
JAK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
125 kDa
Protein Accession #:
NP_004963.1
Protein GI Number:
4826776
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of JAK2 only when phosphorylated at tyrosine 1007.
Swissprot #:
O60674