GAMT Antibody

ProSci
Product Code: PSI-29-621
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-29-621-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GAMT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

Further Information

Additional Names:
GAMT, PIG2, TP53I2, CCDS2, HEL-S-20
Application Note:
GAMT antibody can be used for detection of GAMT by ELISA at 1:62500. GAMT antibody can be used for detection of GAMT by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
Background References:
  • Komoto, J., (1999) Acta Crystallogr. D Biol. Crystallogr. 55 (11), 1928-1929.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GAMT.
NCBI Gene ID #:
2593
NCBI Official Name:
guanidinoacetate N-methyltransferase
NCBI Official Symbol:
GAMT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa, 29 kDa
Protein Accession #:
NP_000147
Protein GI Number:
4503909
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q14353
User NOte:
Optimal dilutions for each application to be determined by the researcher.