AGPAT2 Antibody
| Code | Size | Price |
|---|
| PSI-31-341-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store AGPAT2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
AGPAT2, 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
Application Note:
AGPAT2 antibody can be used for detection of AGPAT2 by ELISA at 1:312500. AGPAT2 antibody can be used for detection of AGPAT2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Background References:
- Niesporek, S., (2005) Br. J. Cancer 92 (9), 1729-1736.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AGPAT2.
NCBI Gene ID #:
10555
NCBI Official Name:
1-acylglycerol-3-phosphate O-acyltransferase 2
NCBI Official Symbol:
AGPAT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa, 31 kDa
Protein Accession #:
NP_001012745
Protein GI Number:
69122971
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
Q5VUD3
User NOte:
Optimal dilutions for each application to be determined by the researcher.