PARP3 Antibody

ProSci
Product Code: PSI-46-753
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-753-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-753 (3.75ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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46-753 (3.75ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Further Information

Additional Names:
PARP3, poly (ADP-ribose) polymerase family, member 3, ADPRT3, ADPRTL2, ADPRTL3, IRT1, hPARP-3, pADPRT-3, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 2, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 3, NAD+ ADP-ribosyltransferase 3, poly(ADP-ribose) polymerase 3, poly(ADP-ribose) synthetase-3
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Preliminary experiments in lysates of cell lines Daudi, HeLa and HepG2 gave no specific signal but low background (at antibody concentration up to 1ug/ml).Immunohistochemistry:Paraffin embedded Human Liver and Kidney. Recommended concentration: 3.75ug/ml.
Background References:
  • Rouleau M, McDonald D, Gagne P, Ouellet ME, Droit A, Hunter JM, Dutertre S, Prigent C, Hendzel MJ, Poirier GG. PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery. J Cell Biochem. 2007 Feb 1;100(2):385-401.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: YEDYNCTLNQTNIEN
NCBI Gene ID #:
10039
NCBI Official Name:
poly (ADP-ribose) polymerase family, member 3
NCBI Official Symbol:
PARP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001003931.2, NP_001003935.2
Protein GI Number:
158634478
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Apoptosis
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_001003931.2; NP_001003935.2).
Swissprot #:
Q9Y6F1