ANXA1 Antibody

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ProSci
Product Code: PSI-28-512
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-28-512-100ul100ul£609.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ANXA1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Intestine.
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Antibody used in WB on mouse fibroblasts at 1:600.
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Antibody used in WB on HepG2 at 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).
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Antibody used in IHC on Human Intestine.
Antibody used in WB on mouse fibroblasts at 1:600.
Antibody used in WB on HepG2 at 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).

Documents

Further Information

Additional Names:
ANXA1, ANX1, LPC1
Application Note:
ANXA1 antibody can be used for detection of ANXA1 by ELISA at 1:62500. ANXA1 antibody can be used for detection of ANXA1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ANXA1 encodes a protein that belongs to a family of Ca (2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
Background References:
  • Ernst, S., et al., (2004) J. Immunol. 172 (12), 7669-7676.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANXA1.
NCBI Gene ID #:
301
NCBI Official Name:
annexin A1
NCBI Official Symbol:
ANXA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
NP_000691
Protein GI Number:
4502101
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer ,Signal Transduction ,Immunology
Swissprot #:
Q5TZZ9
User NOte:
Optimal dilutions for each application to be determined by the researcher.