M6PR Antibody
| Code | Size | Price |
|---|
| PSI-29-879-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store M6PR antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
M6PR, CD-MPR, FLJ32994, MPR46, SMPR, MPR 46, MPR-46
Application Note:
M6PR antibody can be used for detection of M6PR by ELISA at 1:312500. M6PR antibody can be used for detection of M6PR by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Background References:
- Chen, J.J., (2004) Cell 119 (7), 915-926.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human M6PR.
NCBI Gene ID #:
4074
NCBI Official Name:
mannose-6-phosphate receptor (cation dependent)
NCBI Official Symbol:
M6PR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
NP_002346
Protein GI Number:
4505061
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
P20645
User NOte:
Optimal dilutions for each application to be determined by the researcher.