SLC22A2 Antibody

ProSci
Product Code: PSI-29-915
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-29-915-100ul100ul£609.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC22A2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 2.5 ug/ml.

Antibody used in WB on Human HepG2 at 2.5 ug/ml.

Further Information

Additional Names:
SLC22A2, MGC32628, OCT2, 41914
Application Note:
SLC22A2 antibody can be used for detection of SLC22A2 by ELISA at 1:312500. SLC22A2 antibody can be used for detection of SLC22A2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is one of the three similar cation transporters. SLC22A2 contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Two transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Pelis, R.M., Am. J. Physiol. Renal Physiol. 290 (5), F1118-F1126 (2006).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC22A2.
NCBI Gene ID #:
6582
NCBI Official Name:
solute carrier family 22 (organic cation transporter), member 2
NCBI Official Symbol:
SLC22A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
NP_003049
Protein GI Number:
302148518
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane
Swissprot #:
O15244
User NOte:
Optimal dilutions for each application to be determined by the researcher.