ST3GAL5 Antibody
| Code | Size | Price |
|---|
| PSI-30-197-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ST3GAL5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
ST3GAL5, SIAT9, SIATGM3S, ST3GalV, SATI
Application Note:
ST3GAL5 antibody can be used for detection of ST3GAL5 by ELISA at 1:1562500. ST3GAL5 antibody can be used for detection of ST3GAL5 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. ST3GAL5 is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. It is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in its gene has been associated with Amish infantile epilepsy syndrome.Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus.
Background References:
- Chung, T.W., (2005) Glycobiology 15 (3), 233-244.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ST3GAL5.
NCBI Gene ID #:
8869
NCBI Official Name:
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NCBI Official Symbol:
ST3GAL5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa, 46 kDa
Protein Accession #:
NP_003887
Protein GI Number:
109633044
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane
Swissprot #:
Q6NZX4
User NOte:
Optimal dilutions for each application to be determined by the researcher.