TMPRSS11D Antibody

ProSci
Product Code: PSI-30-200
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-30-200-100ul100ul£609.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TMPRSS11D antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Lung.
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Antibody used in IHC on Human Lung.

Further Information

Additional Names:
TMPRSS11D, HAT, MGC150587, MGC150588
Application Note:
TMPRSS11D antibody can be used for detection of TMPRSS11D by ELISA at 1:62500. TMPRSS11D antibody can be used for detection of TMPRSS11D by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Background References:
  • Matsushima, R., Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2), L385-L395 (2006).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMPRSS11D.
NCBI Gene ID #:
9407
NCBI Official Name:
transmembrane protease, serine 11D
NCBI Official Symbol:
TMPRSS11D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
NP_004253
Protein GI Number:
4758508
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
O60235
User NOte:
Optimal dilutions for each application to be determined by the researcher.