ASH2L Antibody
| Code | Size | Price |
|---|
| PSI-79-687-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
ASH2, Bre2, ASH2L1, ASH2L2, ASH2
Application Note:
Western Blot: 1:500~1:1000
Background:
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Background References:
- Wysocka J., Myers M. P., Laherty C. D., Eisenman R. N., Herr W. Genes Dev. 17:896-911 (2003) Patel A., Dharmarajan V., Vought V. E., Cosgrove M. S. J. Biol. Chem. 284:24242-24256 (2009)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ASH2L antibody was raised against a peptide sequence around aa.620~624 (G-R-R-S-P) derived from Human ASH2L.
NCBI Gene ID #:
9070
NCBI Official Name:
ash2 (absent, small, or homeotic)-like (Drosophila)
NCBI Official Symbol:
ASH2L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65, 80 kDa
Protein Accession #:
NP_004665.2
Protein GI Number:
157412280
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total ASH2L protein.
Swissprot #:
Q9UBL3