ASPSCR1 Antibody
| Code | Size | Price |
|---|
| PSI-79-649-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, HSP27, HSP28, TUG
Application Note:
Western Blot: 1:500~1:1000
Background:
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.
Background References:
- Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J. S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ASPSCR1 antibody was raised against a peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.
NCBI Gene ID #:
79058
NCBI Official Name:
alveolar soft part sarcoma chromosome region, candidate 1
NCBI Official Symbol:
ASPSCR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 - 75 kDa
Protein Accession #:
NP_076988.1
Protein GI Number:
13129078
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous levels of total ASPSCR1 protein.
Swissprot #:
Q9BZE9