EGFR Antibody

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ProSci
Product Code: PSI-79-310
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-310-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from HUVEC and MDA cells using EGFR (Ab-1070).
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<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR (Ab-1070).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using EGFR (Ab-1070).
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Western blot analysis of lysed extracts from HUVEC and MDA cells using EGFR (Ab-1070).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR (Ab-1070).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using EGFR (Ab-1070).

Documents

Further Information

Additional Names:
ERBB, HER1, mENA, ERBB1, PIG61, GLUH1, GLUR1, Receptor tyrosine-protein kinase ErbB-1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia
Background References:
  • Feinmesser RL, et al. (1999) J Biol Chem; 274 (23): 16168-73. Gamou S, et al. (1995) FEBS Lett; 357 (2): 161-4. Gamou S, et al. (1994) J Cell Physiol; 158 (1): 151-9. Heisermann GJ, et al. (1988) J Biol Chem; 263 (26): 13152-8.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
EGFR (Ab-1070) antibody was raised against a peptide sequence around aa.1068~1072 (R-Y-S-S-D) derived from Human EGFR.
NCBI Gene ID #:
1956
NCBI Official Name:
epidermal growth factor receptor
NCBI Official Symbol:
EGFR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
175 kDa
Protein Accession #:
NP_005219.2
Protein GI Number:
29725609
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total EGFR protein.
Swissprot #:
P00533