Estrogen Receptor-a Antibody

ProSci
Product Code: PSI-79-303
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-303-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from MCF-7, SK-OV-3 cells and Rat hippocampus tissue using Estrogen Receptor-α (Ab-104).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-α (Ab-104).

Western blot analysis of lysed extracts from MCF-7, SK-OV-3 cells and Rat hippocampus tissue using Estrogen Receptor-α (Ab-104).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-α (Ab-104).

Further Information

Additional Names:
ER, ESR, Era, ESRA, ESTRR, NR3A1, CTNNB, OK/SW-cl.35, PRO2286, ER, ESR1, ESTR, ESTRA
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Background References:
  • Medunjanin S, et al. (2005) . J Biol Chem. 80 (38): 33006-33014. Dutertre M, et al. (2003) . Mol Endocrinol. 17 (7): 1296-1314. Chen D, et al. (2000) . Mol Cell. 6 (1): 127-137. Rogatsky I, et al. (1999) . J Biol Chem. 274 (32): 22296-22302.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Estrogen Receptor-a (Ab-104) antibody was raised against a peptide sequence around aa.102~106 (S-V-S-P-S) derived from Human Estrogen Receptor-α.
NCBI Gene ID #:
2099
NCBI Official Name:
estrogen receptor 1
NCBI Official Symbol:
ESR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
NP_000116.2
Protein GI Number:
62821794
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total Estrogen Receptor-α protein.
Swissprot #:
P03372