Melanoma-associated antigen D1 Antibody
| Code | Size | Price |
|---|
| PSI-79-631-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
NRAGE, Dlixin, Dlxin1, Dlxin-1, MAGE-D1, mFLJ00163, DXBwg1492e, 2810433C11Rik, 5430405L04Rik, MAGED1
Application Note:
Western Blot: 1:500~1:1000
Background:
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
Background References:
- Zhao Z, et al. (2002) Sci China C Life Sci. 45 (4): 412-20. Shen WG, et al. (2007) Cell Commun Adhes. 14 (1): 21-31. Cheresh DA, et al. (1984) J Biol Chem. 259 (12): 7453-9.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Melanoma-associated antigen D1 antibodyPeptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
NCBI Gene ID #:
94275
NCBI Official Name:
melanoma antigen, family D, 1
NCBI Official Symbol:
Maged1
NCBI Organism:
Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
95 kDa
Protein Accession #:
NP_062765.1
Protein GI Number:
9789935
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.
Swissprot #:
Q9QYH6