TRPC6 Antibody
| Code | Size | Price |
|---|
| PSI-79-629-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
TRP6, FSGS2, TRP6, FLJ11098
Application Note:
Western Blot: 1:500~1:1000
Background:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Background References:
- Koichiro Kuwahara et al. (2006) J Clin Invest. 116 (12): 3114?3126. Mark Estacion et al. (2006) J Physiol. 2006, 572 (Pt 2): 359?377. Maria A et al. (2006) Proc Natl Acad Sci U S A. 103 (44): 16586?16591.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TRPC6 antibodypeptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
NCBI Gene ID #:
7225
NCBI Official Name:
transient receptor potential cation channel, subfamily C, member 6
NCBI Official Symbol:
TRPC6
NCBI Organism:
peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
100 kDa
Protein Accession #:
NP_004612.2
Protein GI Number:
5730102
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Swissprot #:
Q61143