KCNA10 Antibody

ProSci
Product Code: PSI-28-252
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-252-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KCNA10 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human kidney.
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Antibody used in IHC on Human kidney.

Further Information

Additional Names:
KCNA10, Kcn1, Kv1.8
Application Note:
KCNA10 antibody can be used for detection of KCNA10 by ELISA at 1:312500. KCNA10 antibody can be used for detection of KCNA10 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Four sequence-related potassium channel genes, shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog (s). KCNA10 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP.
Background References:
  • Yao, X., et al., (2002) J. Am. Soc. Nephrol. 13 (12), 2831-2839.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNA10.
NCBI Gene ID #:
3744
NCBI Official Name:
potassium voltage-gated channel, shaker-related subfamily, member 10
NCBI Official Symbol:
KCNA10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
NP_005540
Protein GI Number:
5031819
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane
Swissprot #:
Q16322
User NOte:
Optimal dilutions for each application to be determined by the researcher.