SGCE Antibody
Code | Size | Price |
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PSI-26-132-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SGCE antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Further Information
Additional Names:
SGCE, DYT11, ESG
Application Note:
SGCE antibody can be used for detection of SGCE by ELISA at 1:312500. SGCE antibody can be used for detection of SGCE by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SGCE is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with myoclonus-dystonia syndrome. Alternative splicing results in multiple transcript variants.The SGCE gene encodes the epsilon member of the sarcoglycan family, transmembrane components of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix.
Background References:
- Hjermind, L.E., (2008) Eur. J. Neurol. 15 (5), 525-529.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SGCE.
NCBI Gene ID #:
8910
NCBI Official Name:
sarcoglycan, epsilon
NCBI Official Symbol:
SGCE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
NP_001092871
Protein GI Number:
150378454
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane
Swissprot #:
B5MDA7
User NOte:
Optimal dilutions for each application to be determined by the researcher.