SMAD4 Antibody

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ProSci
Product Code: PSI-45-148
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-148-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Documents

Further Information

Additional Names:
MADH4, SMAD4, JIP, DPC4, MAD, mothers against decapentaplegic homolog 4 (Drosophila), Mothers against decapentaplegic, Drosophila, homolog of, 4, MAD (mothers against decapentaplegic, Drosophila) homolog 4, SMAD family member 4, OTTHUMP00000163548, SMAD, mothers against DPP homolog 4, deleted in pancreatic carcinoma locus 4, mothers against decapentaplegic homolog 4
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave a band at approx 75kDa in lysates of cell line NIH3T3. Please note that currently we cannot find an explanation in the literatureImmunoprecipitation:This antibody was deemed fit for IP under native conditions (observations from anonymous customer).
Background References:
  • Kim SK, Fan Y, Papadimitrakopoulou V, Clayman G, Hittelman WN, Hong WK, Lotan R, Mao L. DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. Cancer Res 1996 Jun 1;56(11):2519-21
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Dog, Pig Cow
Immunogen:
The immunogen for this antibody is: C-HTMPIADPQPLD
NCBI Gene ID #:
4089
NCBI Official Name:
SMAD family member 4
NCBI Official Symbol:
SMAD4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_005350.1
Protein GI Number:
4885457
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction ,Cancer
SPECIFICITY:
.
Swissprot #:
Q13485