P2RX7 Antibody

ProSci
Product Code: PSI-28-305
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-305-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store P2RX7 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human kidney.
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Antibody used in IHC on Human kidney.

Further Information

Additional Names:
P2RX7, P2X7
Application Note:
P2RX7 antibody can be used for detection of P2RX7 by ELISA at 1:312500. P2RX7 antibody can be used for detection of P2RX7 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Background References:
  • Buell, GN., et al., (1998) Receptors Channels 5(6):347-54.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RX7.
NCBI Gene ID #:
5027
NCBI Official Name:
purinergic receptor P2X, ligand-gated ion channel, 7
NCBI Official Symbol:
P2RX7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
Q4VKI1
Protein GI Number:
74753854
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
Q4VKI1
User NOte:
Optimal dilutions for each application to be determined by the researcher.