VDAC1 Antibody
| Code | Size | Price |
|---|
| PSI-28-243-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store VDAC1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
VDAC1, PORIN, VDAC-1
Application Note:
VDAC1 antibody can be used for detection of VDAC1 by ELISA at 1:312500. VDAC1 antibody can be used for detection of VDAC1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH (-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.
Background References:
- Zheng, Y., et al., (2004) Oncogene 23 (6), 1239-1247.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VDAC1.
NCBI Gene ID #:
7416
NCBI Official Name:
voltage-dependent anion channel 1
NCBI Official Symbol:
VDAC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
NP_003365
Protein GI Number:
4507879
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer ,Apoptosis
Swissprot #:
Q5FVE7
User NOte:
Optimal dilutions for each application to be determined by the researcher.