HTR5A Antibody

ProSci
Product Code: PSI-27-231
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-27-231-100ul100ul£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR5A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

Further Information

Additional Names:
HTR5A, 5-HT5A, MGC138226
Application Note:
HTR5A antibody can be used for detection of HTR5A by ELISA at 1:312500. HTR5A antibody can be used for detection of HTR5A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. HTR5A is a member of 5-hydroxytryptamine (serotonin) receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1213 BC112021.1 1-1213 1214-1342 AC093726.3 158913-159041 1343-1935 AC092628.3 1996-2588 1936-2400 AK094255.1 2447-2911
Background References:
  • Wilkie, M.J., (er) Pharmacogenomics J. (2008) In press.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR5A.
NCBI Gene ID #:
3361
NCBI Official Name:
5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
NCBI Official Symbol:
HTR5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
NP_076917
Protein GI Number:
13236497
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
P47898
User NOte:
Optimal dilutions for each application to be determined by the researcher.