ICMT Antibody

ProSci
Product Code: PSI-26-174
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-26-174-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ICMT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Heart at 0.2-1 ug/ml.

Antibody used in WB on Human Heart at 0.2-1 ug/ml.

Further Information

Additional Names:
ICMT, HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT
Application Note:
ICMT antibody can be used for detection of ICMT by ELISA at 1:1562500. ICMT antibody can be used for detection of ICMT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Background References:
  • Lu, Q., (2007) Am. J. Respir. Cell Mol. Biol. 37 (1), 20-30.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ICMT.
NCBI Gene ID #:
23463
NCBI Official Name:
isoprenylcysteine carboxyl methyltransferase
NCBI Official Symbol:
ICMT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_036537
Protein GI Number:
6912430
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
O60725
User NOte:
Optimal dilutions for each application to be determined by the researcher.