CPNE1 Antibody

ProSci
Product Code: PSI-29-325
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-29-325-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CPNE1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 5.0 ug/ml.
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Antibody used in WB on Human HepG2 at 5.0 ug/ml.

Further Information

Additional Names:
CPNE1, CPN1, COPN1
Application Note:
CPNE1 antibody can be used for detection of CPNE1 by ELISA at 1:312500. CPNE1 antibody can be used for detection of CPNE1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 is a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking.Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Sequence analysis identified multiple alternatively spliced variants in the 5' UTR. All variants encode the same protein.
Background References:
  • Tomsig, J.L., Biochem. J. 378 (PT 3), 1089-1094 (2004).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPNE1.
NCBI Gene ID #:
8904
NCBI Official Name:
copine I
NCBI Official Symbol:
CPNE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa, 59 kDa, 59 kDa, 59 kDa, 59 kDa, 59 kDa, 59 kDa, 59 kDa
Protein Accession #:
NP_003906
Protein GI Number:
197333761
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
RNA Binding
Swissprot #:
Q99829
User NOte:
Optimal dilutions for each application to be determined by the researcher.