PCYOX1 Antibody
| Code | Size | Price |
|---|
| PSI-27-767-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PCYOX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
PCYOX1, PCL1
Application Note:
PCYOX1 antibody can be used for detection of PCYOX1 by ELISA at 1:12500. PCYOX1 antibody can be used for detection of PCYOX1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.
Background References:
- Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCYOX1.
NCBI Gene ID #:
51449
NCBI Official Name:
prenylcysteine oxidase 1
NCBI Official Symbol:
PCYOX1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
NP_057381
Protein GI Number:
166795301
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Signal Transduction
Swissprot #:
Q9UHG3
User NOte:
Optimal dilutions for each application to be determined by the researcher.