CBX1 Antibody
| Code | Size | Price |
|---|
| PSI-28-089-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CBX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
CBX1, CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
Application Note:
CBX1 antibody can be used for detection of CBX1 by ELISA at 1:62500. CBX1 antibody can be used for detection of CBX1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.
Background References:
- Verschure, P.J., et al., (2005) Mol. Cell. Biol. 25 (11), 4552-4564.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX1.
NCBI Gene ID #:
10951
NCBI Official Name:
chromobox homolog 1
NCBI Official Symbol:
CBX1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
NP_006798
Protein GI Number:
5803076
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
P83916
User NOte:
Optimal dilutions for each application to be determined by the researcher.