TET2 Antibody

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ProSci
Product Code: PSI-42-198
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-198-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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42-198 (4ug/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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42-198 (4ug/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Documents

Further Information

Additional Names:
TET2, tet oncogene family member 2, FLJ20032, KIAA1546, MGC125715, OTTHUMP00000161869
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Immunohistochemistry:In paraffin embedded Human Spleen shows nuclear staining in select splenocytes. Recommended concentration: 2-6ug/ml.
Background References:
  • Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, Stevens-Linders E, van Hoogen P, van Kessel AG, Raymakers RA, Kamping EJ, Verhoef GE, Verburgh E, Hagemeijer A, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH, Acquired mutations in TET2 are common in myelodysplastic syndromes. Nature Gen. 2009 Jul 41 (7): 838-42.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Dog
Immunogen:
The immunogen for this antibody is: C-PHPQSNNDQQREGSF
NCBI Gene ID #:
54790
NCBI Official Name:
tet methylcytosine dioxygenase 2
NCBI Official Symbol:
TET2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001120680.1, NP_060098.3
Protein GI Number:
187761317
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Immunology
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3).
Swissprot #:
Q6N021