TPP1 Antibody

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ProSci
Product Code: PSI-42-118
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-118-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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42-118 (0.3ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
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42-118 (0.3ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

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Further Information

Additional Names:
TPP1, tripeptidyl peptidase I, CLN2, GIG1, LPIC, MGC21297, ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease), growth-inhibiting protein 1, lysosomal pepstatin insensitive protease, tripeptidyl aminopeptidase, tripeptidyl-peptidase I
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 65kDa band observed in Human Placenta lysates (calculated MW of 61.2kDa according to NP_000382.3). Recommended concentration: 0.3-1ug/ml.
Background References:
  • Kousi M, Siintola E, Dvorakova L, Vlaskova H, Turnbull J, Topcu M, Yuksel D, Gokben S, Minassian BA, Elleder M, Mole SE, Lehesjoki AE. Mutations in CLN7/MFSD8 are a common cause of variant late-infantile neuronal ceroid lipofuscinosis. Brain : a journal of neurology 2009 Mar 132 (Pt 3): 810-9.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Dog, Cow
Immunogen:
The immunogen for this antibody is: C-TPSVIRKRYNLTSQD
NCBI Gene ID #:
1200
NCBI Official Name:
tripeptidyl peptidase I
NCBI Official Symbol:
TPP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000382.3
Protein GI Number:
5729770
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience
SPECIFICITY:
.
Swissprot #:
O14773