FDFT1 Antibody

ProSci
Product Code: PSI-30-428
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-30-428-100ul100ul£609.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FDFT1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Jurkat cells at 2.5 ug/ml.

Antibody used in WB on Human Jurkat cells at 2.5 ug/ml.

Further Information

Additional Names:
FDFT1, DGPT, ERG9, SQS, SS
Application Note:
FDFT1 antibody can be used for detection of FDFT1 by ELISA at 1:12500. FDFT1 antibody can be used for detection of FDFT1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Do, R., (er) Hum. Mutat. (2008) In press.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FDFT1.
NCBI Gene ID #:
2222
NCBI Official Name:
farnesyl-diphosphate farnesyltransferase 1
NCBI Official Symbol:
FDFT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
NP_004453
Protein GI Number:
67089147
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer
Swissprot #:
P37268
User NOte:
Optimal dilutions for each application to be determined by the researcher.