GRPEL2 Antibody
| Code | Size | Price |
|---|
| PSI-26-723-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GRPEL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
GRPEL2, DKFZp451C205, FLJ23713, FLJ33918, Mt-GrpE#2
Application Note:
GRPEL2 antibody can be used for detection of GRPEL2 by ELISA at 1:312500. GRPEL2 antibody can be used for detection of GRPEL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Background References:
- Naylor, D.J., (1998) J. Biol. Chem. 273 (33), 21169-21177.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRPEL2.
NCBI Gene ID #:
134266
NCBI Official Name:
GrpE-like 2, mitochondrial (E. coli)
NCBI Official Symbol:
GRPEL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
NP_689620
Protein GI Number:
40255109
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q8TAA5
User NOte:
Optimal dilutions for each application to be determined by the researcher.