CRHR1 Antibody

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ProSci
Product Code: PSI-45-431
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-431-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-431 (5ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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45-431 (5ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Documents

Further Information

Additional Names:
CRHR1, CRF-R, corticotropin releasing hormone receptor 1 , CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f , corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor
Application Note:
Peptide ELISA: antibody detection limit dilution 1:1000.Western Blot:This antibody has been successfully used in WB on Mouse: Hunt AJ Jr et al, Brain Struct Funct. 2018 Jul;223(6):2685-2698. PMID: 29569009.Immunohistochemistry:Paraffin embedded Human Brain (Cortex). Recommended concentration: 5ug/ml.Immunofluorescence: Expression of the protein seen in the cytoplasm and endosomes of MCF7 cells. Recommended concentration: 10ug/ml.
Background References:
  • Ungless MA, Singh V, Crowder TL, Yaka R, Ron D, Bonci A. Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. Neuron. 2003 Jul 31;39(3):401-7.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow, Sheep
Immunogen:
The immunogen for this antibody is: KLYYDNEKCWFGKR
NCBI Gene ID #:
1394
NCBI Official Name:
corticotropin releasing hormone receptor 1
NCBI Official Symbol:
CRHR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_004373.2
Protein GI Number:
19923245
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
Swissprot #:
P34998