DISC1 Antibody

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ProSci
Product Code: PSI-45-481
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-481-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-481 (0.1ug/ml) staining of Human Hippocampus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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45-481 (0.1ug/ml) staining of Human Hippocampus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
DISC1, disrupted in schizophrenia 1 , RP4-730B13.1, KIAA0457
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 100kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 93.6kDa according to NP_001012975.1). Recommended concentration: 0.1-0.3ug/ml. Primary incubation 1 hour at room temperature.
Background References:
  • Millar JK, Pickard BS, Mackie S, James R, Christie S, Buchanan SR, Malloy MP, Chubb JE, Huston E, Baillie GS, Thomson PA, Hill EV, Brandon NJ, Rain JC, Camargo LM, Whiting PJ, Houslay MD, Blackwood DH, Muir WJ, Porteous DJ. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science. 2005 Nov 18;310(5751):1187-91.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-HSEDKRKTPLKVLE
NCBI Gene ID #:
27185
NCBI Official Name:
disrupted in schizophrenia 1
NCBI Official Symbol:
DISC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001012975.1, NP_061132.2
Protein GI Number:
61742825
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise isoforms L ( NP_061132.2) and Lv (NP_001012975.1) only.
Swissprot #:
Q9NRI5