Aromatase Antibody

ProSci
Product Code: PSI-45-289
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-289-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-289 (0.1ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.
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45-289 (0.1ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

Further Information

Additional Names:
CYP19A1, cytochrome P450, family 19, subfamily A, polypeptide 1 , ARO, ARO1, CPV1, CYAR, CYP19, MGC104309, P-450AROM, aromataseN: cytochrome P450, family 19, cytochrome P450, subfamily XIX (aromatization of androgens), estrogen synthetase, flavoprotein-linked monooxygenase, microsomal monooxygenase
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 50-55kDa band observed in Human Placenta lysates (calculated MW of 57.9kDa according to NP_000094.2 and NP_112503.1). Recommended concentration: 0.1-0.3ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Placenta. Recommended concentration: 4ug/ml.
Background References:
  • Van Poznak CH, Hayes DF. Aromatase inhibitors for the treatment of breast cancer: is tamoxifen of historical interest only J Natl Cancer Inst. 2006 Sep 20;98(18):1261-3. No abstract available.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-HDLSLHPDETKN
NCBI Gene ID #:
1588
NCBI Official Name:
cytochrome P450, family 19, subfamily A, polypeptide 1
NCBI Official Symbol:
CYP19A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000094.2, NP_112503.1
Protein GI Number:
13904858
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise both reported isoforms (NP_000094.2 and NP_112503.1), which are identical
Swissprot #:
P11511