DTX2 Antibody
| Code | Size | Price |
|---|
| PSI-29-852-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Fish
- Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DTX2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
DTX2, KIAA1528, MGC71098, RNF58
Application Note:
DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.
NCBI Gene ID #:
113878
NCBI Official Name:
deltex 2, E3 ubiquitin ligase
NCBI Official Symbol:
DTX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa
Protein Accession #:
NP_001096066
Protein GI Number:
156564386
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Apoptosis ,Homeostasis
Swissprot #:
Q6XM87
User NOte:
Optimal dilutions for each application to be determined by the researcher.