CaMKII Antibody

ProSci
Product Code: PSI-79-605
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-605-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from HeLa using CaMKII (Ab-286).
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Immunofluorescence staining of paraffin-embedded human hippocampal region tissue from the falling sickness disease using CaMKII (Ab-286).

Western blot analysis of lysed extracts from HeLa using CaMKII (Ab-286).
Immunofluorescence staining of paraffin-embedded human hippocampal region tissue from the falling sickness disease using CaMKII (Ab-286).

Further Information

Additional Names:
CAMKIIN, CAM-KIIN, CAMK2A, CaMKII-alpha
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background:
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity
Background References:
  • J Bossuyt, K Helmstadter, X Wu, et al. (2008) Ca2+/Calmodulin-Dependent Protein Kinase II {delta} and Protein Kinase D Overexpression Reinforce - Circulation Research, 102 (6): 695-702.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CaMKII (Ab-286) antibody was raised against a peptide sequence around aa.284~288 (Q-E-T-V-D) derived from Human CaMKII.
NCBI Gene ID #:
94032
NCBI Official Name:
calcium/calmodulin-dependent protein kinase II inhibitor 2
NCBI Official Symbol:
CAMK2N2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
NP_150284.1
Protein GI Number:
15147234
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total CaMKII protein.
Swissprot #:
P11798